HRID1419652

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10612601

Boronic acid, [4-(decyloxy)phenyl]-

C16H27BO3

结构：CCCCc1ccc2c(c1)C(F)(F)C(F)(F)C1=C2C=CC(Br)C1

HCID54442732

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCCCOc1ccc(-c2ccc3c(c2)C(F)(F)C(F)(F)c2cc(CCCC)ccc2-3)cc1

HCID54561094

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID23938

Palladium

PROCEDURE

实验过程

From 9,9,10,10-tetrafluoro-2-bromo-7-butyldihydrophenanthrene and 4-decyloxyphenylboronic acid by means of palladium-catalyzed Suzuki coupling (in analogy to Acc. Chem. Res. 1982, 15, 178). The crude product is purified by column chromatography.

WORKUP

后处理

customThe crude product is purified by column chromatography

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-18bcf341992a40ba9379444e544c305c
来源数据集: uspto-grants-1999_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05888422
来源说明: uspto-grants-1999_03

反应 SMILES

[F:1][C:2]1([F:23])[C:15]([F:17])([F:16])[C:14]2[CH2:13][CH:12](Br)[CH:11]=[CH:10][C:9]=2[C:8]2[C:3]1=[CH:4][C:5]([CH2:19][CH2:20][CH2:21][CH3:22])=[CH:6][CH:7]=2.[CH2:24]([O:34][C:35]1[CH:40]=[CH:39][C:38](B(O)O)=[CH:37][CH:36]=1)[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33]>[Pd]>[CH2:24]([O:34][C:35]1[CH:36]=[CH:37][C:38]([C:12]2[CH:11]=[CH:10][C:9]3[C:8]4[C:3](=[CH:4][C:5]([CH2:19][CH2:20][CH2:21][CH3:22])=[CH:6][CH:7]=4)[C:2]([F:23])([F:1])[C:15]([F:17])([F:16])[C:14]=3[CH:13]=2)=[CH:39][CH:40]=1)[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33]