HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iometopane → 3b-(4-Iodophenyl)tropane-2b-carboxylic
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iometopane | HCID 108220 | — |
| Solvent | 1,4-Dioxane--water (1/1) | HCID 21886435 | — |
| Product | 3b-(4-Iodophenyl)tropane-2b-carboxylic | HCID 15639797 | — |
Reaction Steps
A round bottom flask filled with a solution of 100 mg of 2β-Carbomethoxy-3β-(4-Iodophenyl)tropane in 10 mL of 1:1 water/dioxane was heated to a gentle reflux for two days. The solvent was then removed and the white residue was triturated with hot ethyl acetate twice. The remaining solid was dried under in vacuo to yield 90 mg of CIT-acid 7, (93%) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05888475 |
| Source dataset | uspto-grants-1999_03 |
| ORD ID | ord-df1fc272bc504d0c9138a3f71a3f28ec |
| Source note | uspto-grants-1999_03 |