3-Methylbutanal → 1,3-Dioxane, 5-methyl-2-(2-methylpropyl)-, cis-

HRID 1419683Notes

Reaction equation

[CH:1](=[O:6])[CH2:2][CH:3]([CH3:5])[CH3:4].[CH3:7][CH:8]([CH2:11]O)[CH2:9][OH:10]>>[CH2:2]([CH:1]1[O:10][CH2:9][CH:8]([CH3:11])[CH2:7][O:6]1)[CH:3]([CH3:5])[CH3:4]

Participants

Reactant 2

HCID 115523-Methylbutanal

HCID 75103Methylpropanediol

Product 1

HCID 235135601,3-Dioxane, 5-methyl-2-(2-methylpropyl)-, cis-

Procedure

2-isobutyl-5-methyl-1,3-dioxane was prepared on a laboratory scale by acid catalysed condensation of isovaleraldehyde and 2-methylpropane-1,3-diol using a 1 litre 3 necked flask equipped with a Dean and Stark condenser, a thermometer and a mechanical stirrer. The reaction scheme is shown in FIG. 1.

Workup

customequipped with a Dean and Stark condenser
customThe reaction scheme

Sources & evidence

ORD record: ord-8cb8587b93e242d4aa5446d37300690c
Source dataset: uspto-grants-1999_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05888961

Reaction notes

Loading…