Piperazine → HCID 21460304, compound

HRID 1419770Notes

Reaction equation

[CH:1]1([N:10]2[C:19]3[C:14](=[CH:15][C:16]([F:22])=[C:17](F)[C:18]=3[F:20])[C:13](=[O:23])[C:12]([C:24]([OH:26])=[O:25])=[CH:11]2)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.[NH:27]1[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1>>[F:22][C:16]1[CH:15]=[C:14]2[C:19](=[C:18]([F:20])[C:17]=1[N:27]1[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1)[N:10]([CH:1]1[C:9]3[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=3)[CH2:3][CH2:2]1)[CH:11]=[C:12]([C:24]([OH:26])=[O:25])[C:13]2=[O:23]

Participants

Reactant 2

HCID 4837Piperazine

HCID 53928286HCID 53928286, compound

Product 1

HCID 21460304HCID 21460304, compound

Procedure

Using 1-(indan-1-yl)-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and piperazine, the same procedure as in Production Example 1 was followed to yield the title compound.

Sources & evidence

ORD record: ord-c3a75fc6cd7d462e895bf50406dde60f
Source dataset: uspto-grants-1999_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05889009

Reaction notes

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