HCID 15860210, compound → HCID 15860211, compound

HRID 1419788Notes

Reaction equation

HRID 1419788 reaction equation
[CH:1]1([O:6][C:7]2[CH:8]=[C:9]([CH2:15][C:16]([NH:18][C:19]3[CH:24]=[C:23]([Cl:25])[CH:22]=[CH:21][C:20]=3[O:26]CC=C)=[O:17])[CH:10]=[CH:11][C:12]=2[O:13][CH3:14])[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:30](OC1C=CC(Cl)=CC=1N)[CH:31]=[CH2:32]>C1(OC2C=CC=CC=2)C=CC=CC=1>[CH:1]1([O:6][C:7]2[CH:8]=[C:9]([CH2:15][C:16]([NH:18][C:19]3[CH:24]=[C:23]([Cl:25])[CH:22]=[C:21]([CH2:32][CH:31]=[CH2:30])[C:20]=3[OH:26])=[O:17])[CH:10]=[CH:11][C:12]=2[O:13][CH3:14])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

4

Reactant 2

HCID 15860210HCID 15860210, compoundHCID 16125026HCID 16125026, compound

Product 1

HCID 15860211HCID 15860211, compound

Reagents, catalysts & solvents 1

HCID 7583Diphenyl EtherSolvent2×

Procedure

A solution of N-(3-cyclopentyloxy4-methoxyphenyl-acetyl)-2-allyloxy-5-chloroaniline (33 grams, 0.079 mol) in 330 millimeters of diphenyl ether was heated at 180° for 6.5 hours. This reaction mixture was combined with a second reaction mixture containing N-3-cyclopentyloxy-4-methoxyphenylacetyl)-2-allyloxy-5-chloroaniline and 250 milliliters of diphenyl ether which had been heated at 180° for 20 hours.

Workup

  1. temperaturehad been heated at 180° for 20 hours

Sources & evidence

ORD record
ord-5c0028439d1947bc84f7a5188e152d52
Source dataset
uspto-grants-1999_03
Patent number
US05889014

Reaction notes

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