反应详情

11.0 g (72.3 mmol) of 4-(1 -methylcyclopropyl)cyclohexanone were stirred for 24 hours with 7.0 g (410 mmol) of NH3 dissolved in 120 ml of methanol, in the presence of 3.0 g of Rh/C (5%) at a hydrogen pressure of 20 bar and at a reaction temperature of 50° C. The reaction solution was filtered and the filtrate was concentrated. 9.8 g (88% of theory) were obtained of a colorless oil which was reacted without further purification.

1. filtrationThe reaction solution was filtered
2. concentrationthe filtrate was concentrated
3. custom9.8 g (88% of theory) were obtained of a colorless oil which
4. customwas reacted without further purification