HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Methanesulfonamidophenoxy)ethyl bromide → N-(4-{2-[4-(4-Chloro-benzyl)-4-hydroxy-piperidin-1-yl]-ethoxy}-phenyl)-methanesulfonamide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Methanesulfonamidophenoxy)ethyl bromide | HCID 11109156 | — |
| Reactant | 4-[(4-Chlorophenyl)methyl]piperidin-4-ol | HCID 22245493 | — |
| Product | N-(4-{2-[4-(4-Chloro-benzyl)-4-hydroxy-piperidin-1-yl]-ethoxy}-phenyl)-methanesulfonamide hydrochloride | HCID 86754006 | — |
Reaction Steps
The title compound, m.p. 74°-77° C. and MS: m/e=439.4 (M+H+), was prepared from 4-(4-chloro-benzyl)-piperidin-4-ol and N-[4-(2-bromoethoxy)-phenyl]-methansulfonamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05889026 |
| Source dataset | uspto-grants-1999_03 |
| ORD ID | ord-0075526a1feb41e3a6d1be8b8c5ed912 |
| Source note | uspto-grants-1999_03 |