HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[(4-Chlorophenyl)methyl]piperidin-4-ol → (RS)-4-(4-Chloro-benzyl)-1-[2-hydroxy-3-(4-hydroxy-phenyl)-propyl]-piperidin-4-ol hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[(4-Chlorophenyl)methyl]piperidin-4-ol | HCID 22245493 | — |
| Reactant | (RS)-4-Oxiranylmethyl-phenol | HCID 53757927 | — |
| Product | (RS)-4-(4-Chloro-benzyl)-1-[2-hydroxy-3-(4-hydroxy-phenyl)-propyl]-piperidin-4-ol hydrochloride | HCID 70054529 | — |
Reaction Steps
The title compound, m.p. 172°-174° C. and MS: m/e=376.4 (M+H+), was prepared from (RS)-4-Oxiranylmethyl-phenol and 4-(4-Chloro-benzyl)-piperidin-4-ol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05889026 |
| Source dataset | uspto-grants-1999_03 |
| ORD ID | ord-17cbf61bb7764c35816114753b33f031 |
| Source note | uspto-grants-1999_03 |