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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1419913Generated: October 29, 2026

4-(4-Methylbenzyl)-piperidin-4-ol → 1-[2-(4-Benzyloxy-phenoxy)-ethyl]-4-(4-methyl-benzyl)-piperidin-4-ol

https://huagongshe.com/reaction/1419913

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Methylbenzyl)-piperidin-4-olHCID 10536242—
Reactant1-(Benzyloxy)-4-(2-bromoethoxy)benzeneHCID 10757088—
Product1-[2-(4-Benzyloxy-phenoxy)-ethyl]-4-(4-methyl-benzyl)-piperidin-4-olHCID 10504454—

Reaction Steps

The title compound, MS: m/e=432.6 (M+H+), was prepared from 1-(2-bromoethoxy)-4-(benzyloxy)-benzene and 4-(4-methyl-benzyl)-piperidin-4-ol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05889026
Source datasetuspto-grants-1999_03
ORD IDord-ec75162aaea94d549970ec39f60ab932
Source noteuspto-grants-1999_03