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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1419916Generated: November 1, 2026

4-[(4-Fluorophenyl)methyl]piperidin-4-ol → 1-[3-(4-Benzyloxy-phenoxy)-propyl]-4-(4-fluoro-benzyl)-piperidin-4-ol

https://huagongshe.com/reaction/1419916

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[(4-Fluorophenyl)methyl]piperidin-4-olHCID 10488624—
Reactant1-(Benzyloxy)-4-(3-bromopropoxy)benzeneHCID 11110031—
Product1-[3-(4-Benzyloxy-phenoxy)-propyl]-4-(4-fluoro-benzyl)-piperidin-4-olHCID 70046971—

Reaction Steps

The title compound, MS: m/e=450.5 (M+H+), was prepared from 1-(3-bromopropoxy)-4-(benzyloxy)-benzene and 4-(4-fluor-benzyl)-piperidin-4-ol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05889026
Source datasetuspto-grants-1999_03
ORD IDord-9128b2a8c87b40b5830b526cbeb67668
Source noteuspto-grants-1999_03