Ammonia → HCID 10608220, compound

HRID 1420296Notes

Reaction equation

HRID 1420296 reaction equation
C[Si](C)(C)[C:3]#[C:4][C:5]1[C:11]([Si](C)(C)C)=[C:10]([OH:16])[C:9]([CH3:17])=[C:8]([CH3:18])[C:6]=1[OH:7].CO.[NH3:23].C(O[CH2:28][CH3:29])(=O)C>>[CH3:3][C:4]1[NH:23][C:28]([CH3:29])=[C:11]2[C:5]=1[C:6](=[O:7])[C:8]([CH3:18])=[C:9]([CH3:17])[C:10]2=[O:16]

Participants

5

Reactant 4

HCID 222AmmoniaHCID 887MethanolHCID 8857Ethyl AcetateHCID 86754018HCID 86754018, compound

Product 1

HCID 10608220HCID 10608220, compoundYield 88%

Procedure

General procedure A was followed using 2 (39.6 mg, 0.12 mmol), 2 mL of methanol saturated with ammonia (large excess). The mixture was stirred at room temperature for 12 h. Column chromatography (20% ethyl acetate in petroleum ether) gave yellow product in 88% yield (21.4 mg). Melting point: Turns black after 290° C. and becomes totally black until 360° C. without melting.

Workup

  1. customTurns black after 290° C.
  2. custombecomes totally black until 360° C.

Sources & evidence

ORD record
ord-d53d710e863f40f39891c354ca03d7c1
Source dataset
uspto-grants-1999_03
Patent number
US05889185

Reaction notes

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