HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithocholic Acid → 5-(2-Adamantylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithocholic Acid | HCID 9903 | — |
| Reactant | 1-Adamantanecarboxylic acid | HCID 13235 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Deoxycholic Acid | HCID 222528 | — |
| Reactant | Potassium Permanganate | HCID 516875 | — |
| Product | 5-(2-Adamantylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione | HCID 726475 | — |
Reaction Steps
As a compound containing both carboxylic acid and hydroxyl group, deoxycholic acid (Compound I, Aldrich reagent) and lithocholic acid (Compound J, Aldrich reagent) were employed. 1-adamantane carboxylic acid was oxidized by making use of an aqueous solution of potassium permanganate, and then mixed with an aqueous solution of sodium hydroxide to synthesized adamantane 1-carboxylic acid 3-ol (Compound K).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06071670 |
| Source dataset | uspto-grants-2000_06 |
| ORD ID | ord-bee8bd4ad0c346788d6fe1a42b08d16e |
| Source note | uspto-grants-2000_06 |