HRID1420483

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

HCID9903

Lithocholic acid

C24H40O3

2 次

HCID13235

1-Adamantane-1-carboxylic acid

C11H16O2

3 次

HCID14798

Sodium Hydroxide

HNaO

结构：C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

HCID222528

Deoxycholic acid

C24H40O4

2 次

HCID516875

Potassium permanganate

KMnO4

PRODUCTS

生成物

结构：CC1(C)OC(=O)C(=C2C3CC4CC(C3)CC2C4)C(=O)O1

HCID726475

5-(2-Adamantylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione

C16H20O4

PROCEDURE

实验过程

As a compound containing both carboxylic acid and hydroxyl group, deoxycholic acid (Compound I, Aldrich reagent) and lithocholic acid (Compound J, Aldrich reagent) were employed. 1-adamantane carboxylic acid was oxidized by making use of an aqueous solution of potassium permanganate, and then mixed with an aqueous solution of sodium hydroxide to synthesized adamantane 1-carboxylic acid 3-ol (Compound K).