m-Chloroperbenzoic acid → HCID 18781964, compound

HRID 1420539Notes

Reaction equation

HRID 1420539 reaction equation
[OH:1][CH2:2][CH2:3][S:4][CH:5]1[N:8]([CH2:9][C:10](=[O:19])[CH2:11][CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[C:7](=[O:20])[CH2:6]1.C1C=C(Cl)C=C(C(OO)=[O:29])C=1>>[OH:1][CH2:2][CH2:3][S:4]([CH:5]1[N:8]([CH2:9][C:10](=[O:19])[CH2:11][CH2:12][C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)[C:7](=[O:20])[CH2:6]1)=[O:29]

Participants

3

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 18782039HCID 18782039, compound

Product 1

HCID 18781964HCID 18781964, compoundYield 20%

Procedure

Treatment of 4-(2-hydroxyethylthio)-N-(4-phenyl-2-oxobutyl)azetidin-2-one with mCPBA as described for Example 17 gave the title compound by crystallisation: white crystals, m.p. 104-5° C., 20% yield

Sources & evidence

ORD record
ord-e801fd922b5f47d79a0b8c16099683a4
Source dataset
uspto-grants-2000_06
Patent number
US06071899

Reaction notes

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