Thionyl Chloride → HCID 70299297, compound

HRID 1420550Notes

Reaction equation

HRID 1420550 reaction equation
O[CH2:2][C:3]1[CH:4]=[C:5]([N:9]2[C:13]3[CH:14]=[CH:15][C:16]([CH3:18])=[CH:17][C:12]=3[N:11]=[CH:10]2)[CH:6]=[CH:7][CH:8]=1.S(Cl)([Cl:21])=O>ClCCl>[ClH:21].[Cl:21][CH2:2][C:3]1[CH:4]=[C:5]([N:9]2[C:13]3[CH:14]=[CH:15][C:16]([CH3:18])=[CH:17][C:12]=3[N:11]=[CH:10]2)[CH:6]=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 18782164HCID 18782164, compound

Product 1

HCID 70299297HCID 70299297, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

1-(3-Hydroxymethylphenyl)-5-methylbenzimidazole (0.3 g, 1.26 mM) was dissolved in dichloromethane (3 ml). Thionyl chloride (92 μl, 1.26 mM) was added and the reaction stirred for 30 minutes. Solvent evaporated to obtain product (0.36 g). MS M+ 957.

Workup

  1. customSolvent evaporated

Sources & evidence

ORD record
ord-58ce5b30868d4b26a0ce586262eb4940
Source dataset
uspto-grants-2000_06
Patent number
US06071909

Reaction notes

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