反应详情

A mixture of 1.0 g (1.97 mmol) of methyl 3-acetoxy-2-[(2-diacetylaminobenzyl)-(4-methoxybenzenesulfonyl)amino]propionate and 0.826 ml (5.92 mmol) of triethylamine in 5 ml of CH2Cl2 was stirred at room temperature overnight. The solution was diluted with 30 ml of CH2Cl2 and washed with 20 ml each of H2O, 2 N citric acid, brine and dried with Na2SO4. The solvent was removed under vacuum to give a brown oil. Anal. for C22H24N2O7S: Calc'd: C,57.4; H,5.3; N,6.1; S,7.0; Found: C,56.2; H,5.5; N,5.6; S,7.2.

1. washwashed with 20 ml each of H2O, 2 N citric acid, brine
2. dry with materialdried with Na2SO4
3. customThe solvent was removed under vacuum
4. customto give a brown oil