反应详情

To a cooled (ice-water bath) mixture of 30% HBr in acetic acid (3 ml) was added 2.5 g 5-methyl-2-nitrobenzyl alcohol and the chilled solution stirred for 2 hours. The mixture was poured into ice-water and extracted with diethyl ether. The extract was washed with H2O, brine and the solvent removed under vacuum to give a mixture of product (50%) and starting material (50%).

1. temperatureTo a cooled
2. extractionextracted with diethyl ether
3. washThe extract was washed with H2O, brine
4. customthe solvent removed under vacuum
5. customto give