Ethyl Bromide → HCID 18782394, compound

HRID 1420655Notes

Reaction equation

[Cl:1][C:2]1[CH:11]=[CH:10][C:9]([Cl:12])=[C:8]2[C:3]=1[CH2:4][CH2:5][CH:6]([N:13]1[CH2:29][CH2:28][C:16]3([N:20]([C:21]4[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=4)[CH2:19][NH:18][C:17]3=[O:27])[CH2:15][CH2:14]1)[CH2:7]2.[CH2:30](Br)[CH3:31]>>[ClH:1].[Cl:1][C:2]1[CH:11]=[CH:10][C:9]([Cl:12])=[C:8]2[C:3]=1[CH2:4][CH2:5][CH:6]([N:13]1[CH2:29][CH2:28][C:16]3([N:20]([C:21]4[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=4)[CH2:19][N:18]([CH2:30][CH3:31])[C:17]3=[O:27])[CH2:15][CH2:14]1)[CH2:7]2

Participants

Reactant 2

HCID 6332Ethyl Bromide

HCID 9954388HCID 9954388, compound

Product 1

HCID 18782394HCID 18782394, compound

Procedure

The title compound, m.p.>250° C. and MS: m/e=458.3, 460.3 (M+H+) was prepared in accordance with general method of example 4 from 8-(5,8-dichloro-1,2,3,4-tetrahydro-2-naphthyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one and ethyl bromide.

Sources & evidence

ORD record: ord-e28f3deecb154515935268f0c2225c2b
Source dataset: uspto-grants-2000_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06071925

Reaction notes

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