Aluminum(III) Chloride → HCID 9904289, compound

HRID 1420771Notes

Reaction equation

HRID 1420771 reaction equation
C[O:2][C:3]1[CH:4]=[C:5]([C:11]2[C:21]3[N:20]4[C:16](=[CH:17][CH:18]=[CH:19]4)[C:15](=[O:22])[C:14]=3[S:13][CH:12]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[Cl-].[Al+3].[Cl-].[Cl-]>C(Cl)(Cl)Cl>[OH:2][C:3]1[CH:4]=[C:5]([C:11]2[C:21]3[N:20]4[C:16](=[CH:17][CH:18]=[CH:19]4)[C:15](=[O:22])[C:14]=3[S:13][CH:12]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]

Participants

4

Reactant 2

HCID 6451240Aluminum(III) ChlorideHCID 9948635HCID 9948635, compound

Product 1

HCID 9904289HCID 9904289, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

A solution of 0.6 mmol of the compound of Example 3 and an excess of aluminium chloride in chloroform is stirred at 50° C. for 30 minutes. After concentration under reduced pressure, the residue is stirred in water for 30 minutes to yield red crystals. After filtration, chromatography on silica gel (chloroform) allows the expected product to be isolated.

Workup

  1. concentrationAfter concentration under reduced pressure
  2. customto yield red crystals
  3. filtrationAfter filtration, chromatography on silica gel (chloroform)
  4. customto be isolated

Sources & evidence

ORD record
ord-e7ce1fff2fd24749add9ebd860db38d4
Source dataset
uspto-grants-2000_06
Patent number
US06071945

Reaction notes

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