Nitromethane → HCID 9927343, compound

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Reaction Steps

A solution of 1 mmol of the compound obtained in Example 12 in 50 ml of nitromethane is stirred for 12 hours at ambient temperature and the reaction mixture is then poured into a 1M potassium hydroxide solution. After extracting with dichloromethane, the organic phases are dried over sodium sulphate, filtered and concentrated under reduced pressure. Chromatography on silica gel (chloroform) allows the expected product to be isolated.

Provenance & Evidence