Ethyl (3,3,5,5-tetramethylcyclohexylidene)acetate → HCID 18783146, compound

HRID 1420869Notes

Reaction equation

HRID 1420869 reaction equation
[CH3:1][C:2]1([CH3:16])[CH2:7][C:6]([CH3:9])([CH3:8])[CH2:5][C:4](=[CH:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH2:3]1>C(O)C.[Pd]>[CH3:8][C:6]1([CH3:9])[CH2:7][C:2]([CH3:1])([CH3:16])[CH2:3][CH:4]([CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH2:5]1

Participants

4

Reactant 1

HCID 15307456Ethyl (3,3,5,5-tetramethylcyclohexylidene)acetate

Product 1

HCID 18783146HCID 18783146, compoundYield 95%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Ethyl 3,3,5,5-tetramethylcyclohexylideneacetate (7) (4.48 g, 20 mmol) in ethanol (100 ml) was hydrogenated over 10% Pd/C (0.22 g, 5 wt. %) at 10 atm for 18 h. Filtration through Celite™ and evaporation afforded 4.28 g (95%) of 8 as an oil.

Workup

  1. filtrationFiltration
  2. customthrough Celite™ and evaporation

Sources & evidence

ORD record
ord-a9b2bd8216d747628cb396fe10c80f73
Source dataset
uspto-grants-2000_06
Patent number
US06071966

Reaction notes

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