Thionyl Chloride → HCID 18783415, compound

HRID 1421104Notes

Reaction equation

HRID 1421104 reaction equation
[C:1]([O:4][C:5]1[C:6]([I:20])=[C:7]([C:11]([I:19])=[C:12]([O:15][C:16](=[O:18])[CH3:17])[C:13]=1[I:14])[C:8](O)=[O:9])(=[O:3])[CH3:2].S(Cl)([Cl:23])=O>C(OCC)(=O)C>[C:1]([O:4][C:5]1[C:6]([I:20])=[C:7]([C:11]([I:19])=[C:12]([O:15][C:16](=[O:18])[CH3:17])[C:13]=1[I:14])[C:8]([Cl:23])=[O:9])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 18783413HCID 18783413, compound

Product 1

HCID 18783415HCID 18783415, compoundYield 88%

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

To a solution of 3,5-diacetoxy-2,4,6-triiodobenzoic acid (9.5 g) in ethyl acetate (80 mL) at 55° C. was added thionyl chloride (5.5 mL) and stirred 5 h. The solution was evaporated and the dry residue crystallized from ethyl acetate to yield 8.6 g (88%) 3,5-diacetoxy-2,4,6-triiodobenzoic acid chloride.

Workup

  1. customThe solution was evaporated
  2. customthe dry residue crystallized from ethyl acetate

Sources & evidence

ORD record
ord-9105b7427d4f4a0b867a3a9ced173919
Source dataset
uspto-grants-2000_06
Patent number
US06072069

Reaction notes

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