反应详情

温度

50 °C

To a mixture of 726g of 2-ethyl-2-hexenal (purity: 99.0%, 5.7 mol), 308 g (3.8 mol) of 37% formalin, and 517 g of methanol heated to 50° C. was added dropwise with stirring 60.8 g (0.38 mol) of a 25% aqueous solution of sodium hydroxide over one hour. After the dropping was completed, the mixture was further stirred at 50° C. for 3 hours. The reaction mixture was analyzed by gas chromatography (the internal standard method with diethylene glycol dimethyl ether as an internal standard), and the yields of 2,4-diethyl-5-hydroxy-2-pentenal and 3,5-diethyl-5,6-dihydro-2H-2-pyranol based on the used formaldehyde and the consumed 2-ethyl-2-hexenal were found to be as follows.

1. additionwas added dropwise