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HRID1421180

反应详情

EQUATION

反应方程式

HRID 1421180 的结构方程式

REACTANTS

反应物

2
结构：CN(C)C=O
HCID6228

N,N-Dimethylformamide

C3H7NO

结构：CC(=O)OCCn1cc(C2=C(c3cn(C)c4ccccc34)C(=O)OC2=O)c2ccccc21
HCID15163046

3-[1-(2-Acetoxyethyl)-3-indolyl]-4-(1-methyl-3-indolyl)furan-2,5-dione

C25H20N2O5

PRODUCTS

生成物

1
结构：Cn1cc(C2=C(c3cn(CCO)c4ccccc34)C(=O)NC2=O)c2ccccc21
HCID5327928

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：N
溶剂HCID222

Ammonia gas

H3N

PROCEDURE

实验过程

A solution of 1.6 g of 3-[1-(2-acetoxyethyl)-3-indolyl]-4-(1-methyl-3-indolyl)furan-2,5-dione in 4 ml of DMF and 8 ml of 33% aqueous ammonia was heated to 160° C. for 4 hours. The precipitate was filtered off and dried to give 1.04 g of 3-[1-(2-hydroxyethyl)-3-indolyl]-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione, m.p. 250°-252° C.

WORKUP

后处理

  1. filtrationThe precipitate was filtered off
  2. customdried