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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 142128Generated: October 29, 2026

Hydrochloric Acid → 2-(4-Tert-butyl-phenyl)-4-fluoro-1-hydroxy-1,2-dihydro-pyrrolo[3,4-c]pyridin-3-one

https://huagongshe.com/reaction/142128

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium ionHCID 923—
ReactantDimethylformamideHCID 6228—
ReactantTetrahydrofuranHCID 8028—
Reactant2,2,6,6-TetramethylpiperidineHCID 13035—
ReactantCarbonate IonHCID 19660—
Reactantn-(4-Tert-butylphenyl)-2-fluoronicotinamideHCID 21959540—
ReactantButyllithiumHCID 178418339—
Product2-(4-Tert-butyl-phenyl)-4-fluoro-1-hydroxy-1,2-dihydro-pyrrolo[3,4-c]pyridin-3-oneHCID 69031989—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-2eba39854f6f4be782e4b83c1196e148
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)