Hydrochloric Acid → 2-(4-Tert-butyl-phenyl)-4-fluoro-1-hydroxy-1,2-dihydro-pyrrolo[3,4-c]pyridin-3-one
Reaction equation
[C:16]([CH3:17])([CH3:18])([CH3:19])[c:20]1[cH:21][cH:22][c:23]([NH:26][C:27]([c:28]2[c:29]([F:34])[n:30][cH:31][cH:32][cH:33]2)=[O:35])[cH:24][cH:25]1.[C:42](=[O:43])([O-:44])[O-:45].[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[CH3:11][CH2:12][CH2:13][CH2:14][Li:15].[CH3:1][C:2]1([CH3:3])[CH2:4][CH2:5][CH2:6][C:7]([CH3:8])([CH3:9])[NH:10]1.[ClH:41].[Na+:46].[Na+:47].[O:36]=[CH:37][N:38]([CH3:39])[CH3:40]>>[C:16]([CH3:17])([CH3:18])([CH3:19])[c:20]1[cH:21][cH:22][c:23]([N:26]2[C:27](=[O:35])[c:28]3[c:29]([F:34])[n:30][cH:31][cH:32][c:33]3[CH:37]2[OH:36])[cH:24][cH:25]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-2eba39854f6f4be782e4b83c1196e148
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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