Ammonia → 2-amino-6-(4-fluoro-3-nitrophenyl)-8-isopropylpyrido[2,3-d]pyrimidin-7(8H)-one
Reaction equation
[F:1][c:2]1[c:3]([N+:24](=[O:25])[O-:26])[cH:4][c:5](-[c:8]2[cH:9][c:10]3[c:11]([n:12][c:13]([S:16][CH3:17])[n:14][cH:15]3)[n:18]([CH:21]([CH3:22])[CH3:23])[c:19]2=[O:20])[cH:6][cH:7]1.[NH3:38].[O:39]1[CH2:40][CH2:41][O:42][CH2:43][CH2:44]1.[OH:27][O:28][C:29]([c:30]1[cH:31][c:32]([Cl:33])[cH:34][cH:35][cH:36]1)=[O:37]>>[F:1][c:2]1[c:3]([N+:24](=[O:25])[O-:26])[cH:4][c:5](-[c:8]2[cH:9][c:10]3[c:11]([n:12][c:13]([NH2:38])[n:14][cH:15]3)[n:18]([CH:21]([CH3:22])[CH3:23])[c:19]2=[O:20])[cH:6][cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-d191335e5b4844c4aba4d78046f43841
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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