HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1421360Generated: October 31, 2026
P-Chloroacetophenone → Benzenemethanol, 4-chloro-alpha-methyl-
https://huagongshe.com/reaction/1421360
Participants
| Role | Name | HCID | Charge |
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| Reactant | P-Chloroacetophenone | HCID 7467 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | Benzenemethanol, 4-chloro-alpha-methyl- | HCID 18825 | — |
Reaction Steps
In a round-bottomed flask provided with magnetic stirrer and reflux condenser or in a 100 ml autoclave, 5.0 g (32.3 mmol) of p-chloroacetophenone, 45 g of isopropyl alcohol and 1.0 g of catalyst were heated under reflux or at 120° C. After the end of the reaction time, the reaction mixture was analyzed by gas chromatography and the yield was determined. The results are summarized in Table 3 below:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06075145 |
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| Source dataset | uspto-grants-2000_06 |
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| ORD ID | ord-b64f969a67b546059b84684b38411f14 |
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| Source note | uspto-grants-2000_06 |
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