Potassium Carbonate → HCID 18779695, compound

Participants

Reaction Steps

2-bromo(5-hydroxymethyl)pyridine (3.00 g, 15.95 mmol), 6-methylpyridone (2.08 g, 19.14 mmol), Copper (2.64, 19.14 mmol) and K2CO3 (0.635 g, 10.0 mmol) were heated at 140° C. for 3 hrs. Added CHC13 to reaction when still warm and let stirred overnight. Filterred the mixture through a frit, concentrated in vacuo and the residue was chromatographed (silica gel, 0-4% MeOH-EtOAc solution). Obtained the title compound as a brown oil.

Provenance & Evidence