HCID 15458389, compound → HCID 18706835, compound

Participants

Reaction Steps

6-Chloro-2,5-diamino-4-[(3-hydroxypropyl)amino]pyrimidine (0.290 g, 1.0 mmol) was dissolved in 20 ml of methanol, and 3 equivalents of 14% HCl-methanol solution was carefully added under ice-cooling. The mixture was warmed to room temperature and the solvent was distilled away to give white crystals (0.26 g, 90.0%), m.p. 120-131° C. (ether).

Provenance & Evidence