Hydrochloric Acid → HCID 57215985, compound

HRID 1422046Notes

Reaction equation

HRID 1422046 reaction equation
[OH:1][C:2]1[CH:12]=[CH:11][C:5]2[C:6](=[O:10])[CH:7]=[CH:8][O:9][C:4]=2[CH:3]=1.[OH:13][C:14]1[CH:15]=[C:16]([CH:19]=[CH:20][C:21]=1[OH:22])[CH:17]=O.Cl.CO>O>[OH:13][C:14]1[CH:15]=[C:16]([CH:17]=[C:8]2[CH2:7][C:6](=[O:10])[C:5]3[CH:11]=[CH:12][C:2]([OH:1])=[CH:3][C:4]=3[O:9]2)[CH:19]=[CH:20][C:21]=1[OH:22]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 87683,4-DihydroxybenzaldehydeHCID 54092797-Hydroxy-4-benzopyrone

Product 1

HCID 57215985HCID 57215985, compoundYield 70.6%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

After 7-hydroxy-4(4H)-benzopyranone 0.5 g and 3,4-dihydroxybenzaldehyde 0.42 g were added to a mixture of concentrated hydrochloric acid 25 ml and methanol 35 ml, the mixture was refluxed for 2.5 hours and cooled to room temperature, and water 250 ml was added. The mixture was allowed to stand for 18 hours and the precipitated crystals were filtered. The crystals were dried over phosphorous pentoxide for four hours under reduced pressure to obtain the desired compound 0.61 g.

Workup

  1. temperaturethe mixture was refluxed for 2.5 hours
  2. filtrationthe precipitated crystals were filtered
  3. dry with materialThe crystals were dried over phosphorous pentoxide for four hours under reduced pressure

Sources & evidence

ORD record
ord-ae2fd8de18134c1ba8628f1ffa0fd72b
Source dataset
uspto-grants-2000_06
Patent number
US06080781

Reaction notes

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