Hydrochloric Acid → HCID 53889305, compound

HRID 1422047Notes

Reaction equation

HRID 1422047 reaction equation
[OH:1][C:2]1[CH:12]=[CH:11][C:5]2[C:6](=[O:10])[CH:7]=[CH:8][O:9][C:4]=2[CH:3]=1.[CH:13]1[C:18]([CH:19]=O)=[CH:17][C:16]2[O:21][CH2:22][O:23][C:15]=2[CH:14]=1.Cl.CO>O>[OH:1][C:2]1[CH:12]=[CH:11][C:5]2[C:6](=[O:10])[C:7](=[CH:19][C:18]3[CH:13]=[CH:14][C:15]4[O:23][CH2:22][O:21][C:16]=4[CH:17]=3)[CH2:8][O:9][C:4]=2[CH:3]=1

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 8438PiperonalHCID 54092797-Hydroxy-4-benzopyrone

Product 1

HCID 53889305HCID 53889305, compoundYield 14.6%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

After 7-hydroxy-4(4H)-benzopyranone 1.0 g and piperonal 1.0 g were added to a mixture of concentrated hydrochloric acid 50 ml and methanol 75 ml, the mixture was refluxed for two hours and cooled to room temperature, and water 200 ml was added. The mixture was allowed to stand for one hour and the precipitated crystals were filtered. The crystals were dried over phosphorous pentoxide for four hours under reduced pressure to obtain the desired compound 0.266 g.

Workup

  1. temperaturethe mixture was refluxed for two hours
  2. filtrationthe precipitated crystals were filtered
  3. dry with materialThe crystals were dried over phosphorous pentoxide for four hours under reduced pressure

Sources & evidence

ORD record
ord-576969fe34de43ec8254607a24fc98bb
Source dataset
uspto-grants-2000_06
Patent number
US06080781

Reaction notes

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