HCID 18706700, compound → HCID 18706463, compound

HRID 1422223Notes

Reaction equation

HRID 1422223 reaction equation
[Br:1][C:2]1[CH:11]=[C:10]2[C:5]([N:6]=[C:7]([O:14]C)[C:8]([O:12]C)=[N:9]2)=[C:4]([CH2:16][OH:17])[CH:3]=1>C(O)(=O)C.Cl>[Br:1][C:2]1[CH:11]=[C:10]2[C:5]([NH:6][C:7](=[O:14])[C:8](=[O:12])[NH:9]2)=[C:4]([CH2:16][OH:17])[CH:3]=1

Participants

4

Reactant 1

HCID 18706700HCID 18706700, compound

Product 1

HCID 18706463HCID 18706463, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 313Hydrochloric AcidSolvent

Conditions

Temperature
20 °C

Procedure

450 mg (1.5 mmol) of 7-bromo-5-hydroxymethyl-2,3-dimethoxy-quinoxaline are dissolved in 30 ml of acetic acid and 10 ml of 2N hydrochloric acid, and the solution is heated at reflux for 2 hours and cooled to 20° C. The solid is filtered off, washed with water and dried.

Workup

  1. temperatureat reflux for 2 hours
  2. filtrationThe solid is filtered off
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-9343ad2511014d1eb79dc892c8ed58e1
Source dataset
uspto-grants-2000_06
Patent number
US06080743

Reaction notes

Loading…