HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → N-(7-Bromo-2,3-dimethoxyquinoxalin-5-ylmethyl)-oxalamic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | N-(7-bromo-2,3-dimethoxy-quinoxalin-5-ylmethyl)-oxalamic acid ethyl ester | HCID 54297612 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | N-(7-Bromo-2,3-dimethoxyquinoxalin-5-ylmethyl)-oxalamic acid | HCID 18706444 | — |
Reaction Steps
276 mg of N-(7-bromo-2,3-dimethoxy-quinoxalin-5-ylmethyl)-oxalamic acid ethyl ester and 150 mg of potassium carbonate are suspended in 2 ml of water and 5 ml of methanol. The mixture is stirred for 20 hours and acidified with 1 N HCl, and the solid is filtered off and washed with methanol and diethyl ether. M.p.>300° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06080743 |
| Source dataset | uspto-grants-2000_06 |
| ORD ID | ord-34cd457fe3404f18af1c006d095a5696 |
| Source note | uspto-grants-2000_06 |