Hydrogen Bromide → HCID 18706524, compound

HRID 1422256Notes

Reaction equation

HRID 1422256 reaction equation
[Br-:1].[NH2:2][C:3]1[CH:8]=[CH:7][N+:6]([CH2:9][C:10]2[CH:19]=[C:18]([N+:20]([O-:22])=[O:21])[CH:17]=[C:16]3[C:11]=2[N:12]=[C:13]([O:25]C)[C:14]([O:23]C)=[N:15]3)=[CH:5][CH:4]=1.Br>C(O)(=O)C.C(OCC)C>[Br-:1].[N+:20]([C:18]1[CH:17]=[C:16]2[C:11]([NH:12][C:13](=[O:25])[C:14](=[O:23])[NH:15]2)=[C:10]([CH2:9][N+:6]2[CH:5]=[CH:4][C:3]([NH2:2])=[CH:8][CH:7]=2)[CH:19]=1)([O-:22])=[O:21]

Participants

5

Reactant 2

HCID 260Hydrogen BromideHCID 18706378HCID 18706378, compound

Product 1

HCID 18706524HCID 18706524, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 3283Diethyl EtherSolvent

Procedure

212 mg (0.5 mmol) of 4-amino-1-(2,3-dimethoxy-7-nitro-quinoxalin-5-yl methyl)-pyridinium bromide are stirred in 3 ml of a 48% solution of hydrogen bromide in glacial acetic acid for 18 hours at room temperature. The brownish reaction mixture is diluted with 7 ml of diethyl ether and then stirred for 10 minutes. The resulting solid is filtered off, washed with a small amount of diethyl ether and dried. The title compound is obtained in the form of a yellow solid having a melting point of>245° C. (decomp.).

Workup

  1. customThe brownish reaction mixture
  2. filtrationThe resulting solid is filtered off
  3. washwashed with a small amount of diethyl ether
  4. customdried

Sources & evidence

ORD record
ord-fd5926c9d4b5410ea61ec1ed8a659384
Source dataset
uspto-grants-2000_06
Patent number
US06080743

Reaction notes

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