Isopropyl iodide → 4,6-Dichloro-1-(1-methylethyl)-1H-imidazo[4,5-c]pyridine

Participants

Reaction Steps

Following the procedure of Example 15b, 4,6-dichloro-1H-imidazo[4,5-c]pyridine (J. Het. Chem. 1965, 196-201) (0.19 g, 1.0 mmol) was reacted with 2-iodopropane. The residue was purified by silica gel chromatography (25 to 35% ethyl acetate in hexane eluant) to afford the title compound as a solid. MS m/z 230.2 (M+1).

Provenance & Evidence