HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4H,5H,6H,7H-(1,3)thiazolo(5,4-c)pyridine → {(S)-6-[(R)-4-(6,7-Dihydro-thiazolo[5,4-c]pyridin-5-ylmethyl)-5-trifluoromethyl-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4H,5H,6H,7H-(1,3)thiazolo(5,4-c)pyridine | HCID 21941992 | — |
| Edukt | {(S)-6-[(R)-4-Bromomethyl-5-trifluoromethyl-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester | HCID 86700813 | — |
| Produkt | {(S)-6-[(R)-4-(6,7-Dihydro-thiazolo[5,4-c]pyridin-5-ylmethyl)-5-trifluoromethyl-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester | HCID 90313454 | — |
Reaktionsschritte
The title compound is prepared from {(S)-6-[(R)-4-bromomethyl-5-trifluoromethyl-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester and 4,5,6,7-tetrahydro-thiazolo[5,4-c]pyridine following a procedure analogous to that described for Intermediate 42. LC (method 1): tR=1.16 min; Mass spectrum (ESI+): m/z=545 [M+H]+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08927531B2 |
| Quelldatensatz | uspto-grants-2015_01 |
| ORD ID | ord-2dd6de7abafd42c7b48e350cf4cbbd68 |
| Quellennotiz | uspto-grants-2015_01 |