2-Methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-C]pyridine → {(S)-6-[(R)-4-(2-Methyl-2,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-5-ylmethyl)-5-trifluoromethyl-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester

Participants

Reaction Steps

The title compound is prepared from {(S)-6-[(R)-4-bromomethyl-5-trifluoromethyl-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester and 2-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine following a procedure analogous to that described for Intermediate 42. LC (method 1): tR=0.92 min; Mass spectrum (ESI+): m/z=542 [M+H]+.

Provenance & Evidence