Calcium Carbonate → HCID 53468631, compound

HRID 1422832Notes

Reaction equation

HRID 1422832 reaction equation
[CH3:1][O:2][C:3]1[C:4]([O:18][CH2:19][CH2:20][CH2:21][N:22]2[C:34]3[CH:33]=[CH:32][CH:31]=[CH:30][C:29]=3[C:28]3[C:23]2=[CH:24][CH:25]=[CH:26][CH:27]=3)=[CH:5][C:6]2[N:12]=[CH:11][C@@H:10]3[CH2:13][CH2:14][CH2:15][N:9]3[C:8](=[O:16])[C:7]=2[CH:17]=1.[C:35]([O-:38])([O-])=O.[Ca+2]>C(#N)C.O.Cl[Hg]Cl>[CH3:1][O:2][C:3]1[C:4]([O:18][CH2:19][CH2:20][CH2:21][N:22]2[C:23]3[CH:24]=[CH:25][C:26]([C:6]4[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:17][CH:7]=4)=[CH:27][C:28]=3[C:29]3[C:34]2=[CH:33][CH:32]=[C:31]([C:24]2[CH:23]=[CH:28][C:27]([O:38][CH3:35])=[CH:26][CH:25]=2)[CH:30]=3)=[CH:5][C:6]2[N:12]=[CH:11][C@@H:10]3[CH2:13][CH2:14][CH2:15][N:9]3[C:8](=[O:16])[C:7]=2[CH:17]=1

Participants

5

Reactant 2

HCID 10112Calcium CarbonateHCID 53468223HCID 53468223, compound

Product 1

HCID 53468631HCID 53468631, compoundYield 58%

Reagents, catalysts & solvents 2

HCID 24085Mercuric ChlorideCatalystHCID 18373917Acetonitrile--water (1/1)Solvent

Procedure

This compound was prepared according to the method described for the compound 6a employing 9d (764.89 mg, 1.0 mmol) and HgCl2 (582 mg, 2.26 mmol), CaCO3 (230 mg, 2.46 mmol) in acetonitrile-water (4:1) to obtain the pure product 10d (373 mg, 58% yield).

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-088604227a034f529999bd8e20fbb6ee
Source dataset
uspto-grants-2015_01
Patent number
US08927538B2

Reaction notes

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