Hydrochloric Acid → HCID 66727435, compound

Participants

Reaction Steps

To a solution of 2-methyl-propane-2-sulfinic acid [(S)-1-(6-methanesulfonyl-pyridin-3-yl)-propyl]-amide (50.0 g, 157 mmol) in methanol (500 mL) is added a 4 N solution of HCl in dioxane (40 mL, 160 mmol). After 1 hour, the mixture is concentrated to near dryness (about 40 mL) and the resulting mixture is diluted with ether (500 mL) and the solid is collected by filtration to afford the title compound.

Provenance & Evidence