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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1423176Generated: November 1, 2026

Imidazole-4-acetic acid → HCID 178491981, compound

https://huagongshe.com/reaction/1423176

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazole-4-acetic acidHCID 96215—
Reactant(S)-3-benzyl-1-(3-(difluoromethoxy)-4-methoxyphenyl)piperazineHCID 52920372—
ProductHCID 178491981HCID 178491981—

Reaction Steps

Prepared by the method outlined for Example 189 using (1H-imidazol-4-yl)-acetic acid and (S)3-benzyl-1-(3-difluoromethoxy-4-methoxy-phenyl)-piperazine (Example 69, Compound 157) as starting materials. Product as an oil. LC/MS (Method B) 3.14 min, [M+1]+ 457. Potency class C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08927546B2
Source datasetuspto-grants-2015_01
ORD IDord-34e5aee55e8f4023be2a3226e39e90d2
Source noteuspto-grants-2015_01