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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1423186Generated: November 2, 2026

Imidazole-4-acetic acid → HCID 178445828, compound

https://huagongshe.com/reaction/1423186

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazole-4-acetic acidHCID 96215—
ReactantHCID 58189099HCID 58189099—
ProductHCID 178445828HCID 178445828—

Reaction Steps

Prepared by the method outlined for Example 189 using 2-(1H-imidazol-4-yl)acetic acid and (S)-1-(3-cyclopropylmethoxy-4-difluoromethoxy-phenyl)-3-isobutyl-piperazine (Example 37, Compound 125) as starting materials. Product as an off-white solid (14%). LC/MS (Method B) 2.94 min, [M+1]+ 463.0. Potency class B.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08927546B2
Source datasetuspto-grants-2015_01
ORD IDord-3736f7ca8cf140a8849bdfc9fe2bf56c
Source noteuspto-grants-2015_01