HRID1423237

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7019477

(5-Methyl-1H-1,2,4-triazol-3-yl)acetic acid

C5H7N3O2

结构：COc1ccc(N2CCN[C@@H](Cc3ccccc3)C2)c2ccc(C(F)(F)F)nc12

HCID58188941

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(N2CCN(C(=O)Cc3nc(C)n[nH]3)[C@@H](Cc3ccccc3)C2)c2ccc(C(F)(F)F)nc12

HCID178491985

未命名化合物

收率 12%

PROCEDURE

实验过程

Prepared using the same procedure described in Example 189 from 5-((S)-3-benzyl-piperazin-1-yl)-8-methoxy-2-trifluoromethyl-quinoline and (5-methyl-1H-[1,2,4]triazol-3-yl)-acetic acid to afford the title compound as colorless solid (17 mg, 12%). LC/MS (Method B) 3.22 min, [M+1]+ 525.

WORKUP

后处理

customPrepared