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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1423237Generated: October 31, 2026

2-(3-methyl-1H-1,2,4-triazol-5-yl)acetic acid → HCID 178491985, compound

https://huagongshe.com/reaction/1423237

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-methyl-1H-1,2,4-triazol-5-yl)acetic acidHCID 7019477—
Reactant(S)-5-(3-benzylpiperazin-1-yl)-8-methoxy-2-(trifluoromethyl)quinolineHCID 58188941—
ProductHCID 178491985HCID 17849198512%

Reaction Steps

Prepared using the same procedure described in Example 189 from 5-((S)-3-benzyl-piperazin-1-yl)-8-methoxy-2-trifluoromethyl-quinoline and (5-methyl-1H-[1,2,4]triazol-3-yl)-acetic acid to afford the title compound as colorless solid (17 mg, 12%). LC/MS (Method B) 3.22 min, [M+1]+ 525.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08927546B2
Source datasetuspto-grants-2015_01
ORD IDord-eadb0889cffd42c6a1c427775c1132b5
Source noteuspto-grants-2015_01