Bromomethylcyclopropane → 1185836-83-2
Reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([F:8])[C:5]([O:9][CH3:10])=[CH:4][C:3]=1[OH:11].Br[CH2:13][CH:14]1[CH2:16][CH2:15]1>>[Br:1][C:2]1[CH:7]=[C:6]([F:8])[C:5]([O:9][CH3:10])=[CH:4][C:3]=1[O:11][CH2:13][CH:14]1[CH2:16][CH2:15]1Participants
3
Procedure
Starting from 2-bromo-4-fluoro-5-methoxy-phenol (example B.a2) and commercially available bromomethyl-cyclopropane the title compound is obtained as colorless solid.
Sources & evidence
- ORD record
- ord-0e5e4a6625884a8f84bc1241dff6e19e
- Source dataset
- uspto-grants-2015_01
- Patent number
- US08927557B2
Reaction notes
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