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HRID1423863

反应详情

EQUATION

反应方程式

HRID 1423863 的结构方程式

REACTANTS

反应物

2
结构：CC(C)=O.O
HCID18366337

Propan-2-one--water (1/1)

C3H8O2

结构：Cl.NCC(=O)N1C[C@H](NC(=O)c2ccccc2)C[C@H]1C(=O)O
HCID44563896

Glycyl-(4R)-4-benzamido-L-proline--hydrogen chloride (1/1)

C14H18ClN3O4

PRODUCTS

生成物

1
结构：Cl.NCC(=O)N1C[C@H](NC(=O)c2ccccc2)C[C@H]1C(=O)O.O
HCID68515358

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)O.COC(C)(C)C
溶剂HCID86616950

未命名化合物

PROCEDURE

实验过程

60.5 mg of amorphous (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid hydrochloride was dissolved in 0.3 mL isopropanol/t-butyl methyl ether (7:3 ratio by volume) and 2.0 mL acetone/water (19:1 ratio by volume) mixed solvent system at room temperature. The container was left open, and the crystals that had formed were collected. The crystalline solid was dried at 40-50° C. under vacuum to give crystalline (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid hydrochloride monohydrate.

WORKUP

后处理

  1. waitThe container was left open
  2. customthe crystals that had formed
  3. customwere collected
  4. customThe crystalline solid was dried at 40-50° C. under vacuum