HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Tert-butylbenzene-1,2-diamine → HCID 178440688, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Tert-butylbenzene-1,2-diamine | HCID 432708 | — |
| Reactant | (2S,4R)-1-[(tert-butoxy)carbonyl]-4-fluoropyrrolidine-2-carboxylic acid | HCID 12043048 | — |
| Product | HCID 178440688 | HCID 178440688 | — |
Reaction Steps
The title compound was prepared according to Method 4 using N-Boc-trans-4-fluoro-L-proline and 4-tert-butyl-1,2-diaminobenzene. The final residue was washed with ethyl acetate and diluted with water, basified with saturated lithium hydroxide solution (pH=8), extracted with ethyl acetate and dried over anhydrous Na2SO4 and concentrated under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08927587B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-2a1ba7b83fa745fb8357dc8846e19630 |
| Source note | uspto-grants-2015_01 |