HCID 57660946, compound → HCID 57660944, compound

HRID 1424313Notes

Reaction equation

HRID 1424313 reaction equation
[CH3:1][O:2][C:3](=[O:44])[CH:4]([NH:33]C(OCC1C=CC=CC=1)=O)[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([N:12]2[CH2:17][CH2:16][CH:15]([CH2:18][N:19]([C:26]([O:28][C:29]([CH3:32])([CH3:31])[CH3:30])=[O:27])[C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=3)[CH2:14][CH2:13]2)=[CH:8][CH:7]=1>CO.[Pd]>[CH3:1][O:2][C:3](=[O:44])[CH:4]([NH2:33])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([N:12]2[CH2:17][CH2:16][CH:15]([CH2:18][N:19]([C:26]([O:28][C:29]([CH3:30])([CH3:31])[CH3:32])=[O:27])[C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=3)[CH2:14][CH2:13]2)=[CH:8][CH:7]=1

Participants

4

Reactant 1

HCID 57660946HCID 57660946, compound

Product 1

HCID 57660944HCID 57660944, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

1.3 g (2.16 mmol) of (3) and 130 mg Pd/C (10%) in 50 ml methanol were stirred under a hydrogen atmosphere for 3 h. The reaction mixture was filtered over a pad of Celite and the solvent was evaporated to give crude (4) as oil which was used without further purification.

Workup

  1. filtrationThe reaction mixture was filtered over a pad of Celite
  2. customthe solvent was evaporated

Sources & evidence

ORD record
ord-0cb63dffae5446d885256256befcc0c4
Source dataset
uspto-grants-2015_01
Patent number
US08927534B2

Reaction notes

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