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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1424628Generated: November 1, 2026

Maleic Anhydride → HCID 66953879, compound

https://huagongshe.com/reaction/1424628

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMaleic AnhydrideHCID 7923—
ReactantN-(2-adamantyl)-2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-1'-carboxamideHCID 25064399—
ProductHCID 66953879HCID 66953879—

Reaction Steps

The title compound was prepared from N-(2-adamantyl)-2,3-dihydro-1H-spiro[isoquinoline-4,4′-piperidine]-1′-carboxamide and maleic anhydride following a procedure analogous to that described in Example 90. LC-MS Method 1 tR=1.7 min, m/z=478; 1H NMR (CDCl3) 1.60-2.20 (18H), 3.11 (m, 2H), 3.58 (s, 2H), 3.92 (br s, 4H), 4.39 (s, 2H), 5.00 (br s, 1H), 6.30-7.45 (6H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08927715B2
Source datasetuspto-grants-2015_01
ORD IDord-4cb16fe5dd8342b9bbeaf83614d3c9ae
Source noteuspto-grants-2015_01