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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1424642Generated: November 2, 2026

Ammonia → HCID 46231720, compound

https://huagongshe.com/reaction/1424642

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantHCID 46216689HCID 46216689—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 46231720HCID 46231720—

Reaction Steps

The title compound was prepared from (±)-2-(7-bromo-1′-((2-adamantyl)carbamoyl)-2,3-dihydrospiro[indene-1,4′-piperidine]-3-yl)acetic acid following a procedure analogous to that described in Example 127 except that 0.5 M NH3 in dioxane was used in place of NH3 gas.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08927715B2
Source datasetuspto-grants-2015_01
ORD IDord-02484162990944babd0dfc9f9f84b1ae
Source noteuspto-grants-2015_01